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Targeting IgG Autoantibodies for Improved Cytotoxicity of Bactericidal Permeability Increasing Protein in Cystic Fibrosis

In people with cystic fibrosis (PWCF), inflammation with concurrent infection occurs from a young age and significantly influences lung disease progression. Studies indicate that neutrophils are important effector cells in the pathogenesis of CF and in the development of anti-neutrophil cytoplasmic...

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Détails bibliographiques
Publié dans:Front Pharmacol
Auteurs principaux: McQuillan, Karen, Gargoum, Fatma, Murphy, Mark P., McElvaney, Oliver J., McElvaney, Noel G., Reeves, Emer P.
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7379883/
https://ncbi.nlm.nih.gov/pubmed/32765284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.01098
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