DeepCAGE transcriptomics identify HOXD10 as a transcription factor regulating lymphatic endothelial responses to VEGF-C

Lymphangiogenesis plays a crucial role during development, in cancer metastasis and in inflammation. Activation of VEGFR-3 (also known as FLT4) by VEGF-C is one of the main drivers of lymphangiogenesis, but the transcriptional events downstream of VEGFR-3 activation are largely unknown. Recently, we...

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Publicado en:J Cell Sci
Autores principales: Klein, Sarah, Dieterich, Lothar C., Mathelier, Anthony, Chong, Chloé, Sliwa-Primorac, Adriana, Hong, Young-Kwon, Shin, Jay W., Lizio, Marina, Itoh, Masayoshi, Kawaji, Hideya, Lassmann, Timo, Daub, Carsten O., Arner, Erik, Carninci, Piero, Hayashizaki, Yoshihide, Forrest, Alistair R. R., Wasserman, Wyeth W., Detmar, Michael
Formato: Artigo
Lenguaje:Inglês
Publicado: The Company of Biologists Ltd 2016
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7376900/
https://ncbi.nlm.nih.gov/pubmed/27199372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.186767
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