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Transition to naïve human pluripotency mirrors pan-cancer DNA hypermethylation
Epigenetic reprogramming is a cancer hallmark, but how it unfolds during early neoplastic events and its role in carcinogenesis and cancer progression is not fully understood. Here we show that resetting from primed to naïve human pluripotency results in acquisition of a DNA methylation landscape mi...
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| Pubblicato in: | Nat Commun |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7376100/ https://ncbi.nlm.nih.gov/pubmed/32699299 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17269-3 |
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