RAS Regulates the Transition from Naive to Primed Pluripotent Stem Cells

The transition from naive to primed state of pluripotent stem cells is hallmarked by epithelial-mesenchymal transition, metabolic switch from oxidative phosphorylation to aerobic glycolysis, and changes in the epigenetic landscape. Since these changes are also seen as putative hallmarks of neoplasti...

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Veröffentlicht in:Stem Cell Reports
Hauptverfasser: Altshuler, Anna, Verbuk, Mila, Bhattacharya, Swarnabh, Abramovich, Ifat, Haklai, Roni, Hanna, Jacob H., Kloog, Yoel, Gottlieb, Eyal, Shalom-Feuerstein, Ruby
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5918191/
https://ncbi.nlm.nih.gov/pubmed/29456180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2018.01.004
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