Reorganization of enhancer patterns in transition from naïve to primed pluripotency

Naïve and primed pluripotency is characterized by distinct signaling requirements, transcriptomes and developmental properties, but both cellular states share key transcriptional regulators, Oct4, Sox2 and Nanog. Here we demonstrate that transition between these two pluripotent states is associated...

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Udgivet i:Cell Stem Cell
Main Authors: Buecker, Christa, Srinivasan, Rajini, Wu, Zhixiang, Calo, Eliezer, Acampora, Dario, Faial, Tiago, Simeone, Antonio, Tan, Minjia, Swigut, Tomasz, Wysocka, Joanna
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491504/
https://ncbi.nlm.nih.gov/pubmed/24905168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2014.04.003
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