Epitope-based sieve analysis of Plasmodium falciparum sequences from a FMP2.1/AS02(A) vaccine trial is consistent with differential vaccine efficacy against immunologically relevant AMA1 variants.

To prevent premature dismissal of promising vaccine programs, it is critical to determine if lack of efficacy in the field is due to allele specific-efficacy, rather than to the lack of immunogenicity of the candidate antigen. Here we use samples collected during a field trial of the AMA1-based FMP2...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Vaccine
Main Authors: Ouattara, Amed, Niangaly, Amadou, Adams, Matthew, Coulibaly, Drissa, Kone, Abdoulaye K., Traore, Karim, Laurens, Matthew B., Tolo, Youssouf, Kouriba, Bourema, Diallo, Dapa A., Doumbo, Ogobara K., Plowe, Christopher V., Djimdé, Abdoulaye, Thera, Mahamadou A., Laufer, Miriam K., Takala-Harrison, Shannon, Silva, Joana C.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2020
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7375901/
https://ncbi.nlm.nih.gov/pubmed/32571720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2020.06.035
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים