Dynamics of Polymorphism in a Malaria Vaccine Antigen at a Vaccine-Testing Site in Mali

BACKGROUND: Malaria vaccines based on the 19-kDa region of merozoite surface protein 1 (MSP-1(19)) derived from the 3D7 strain of Plasmodium falciparum are being tested in clinical trials in Africa. Knowledge of the distribution and natural dynamics of vaccine antigen polymorphisms in populations in...

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Main Authors: Takala, Shannon L, Coulibaly, Drissa, Thera, Mahamadou A, Dicko, Alassane, Smith, David L, Guindo, Ando B, Kone, Abdoulaye K, Traore, Karim, Ouattara, Amed, Djimde, Abdoulaye A, Sehdev, Paul S, Lyke, Kirsten E, Diallo, Dapa A, Doumbo, Ogobara K, Plowe, Christopher V
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1820605/
https://ncbi.nlm.nih.gov/pubmed/17355170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0040093
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