טוען...
Inhibition of post-termination ribosome recycling at premature termination codons in UPF1 ATPase mutants
Recognition and rapid degradation of mRNA harboring premature translation termination codons (PTCs) serves to protect cells from accumulating non-functional and potentially toxic truncated polypeptides. Targeting of PTC-containing transcripts is mediated by the nonsense-mediated mRNA decay (NMD) pat...
שמור ב:
| הוצא לאור ב: | eLife |
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| Main Authors: | , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
eLife Sciences Publications, Ltd
2020
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7375815/ https://ncbi.nlm.nih.gov/pubmed/32697194 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.57834 |
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