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When a ribosome encounters a premature termination codon
In mammalian cells, aberrant transcripts harboring a premature termination codon (PTC) can be generated by abnormal or inefficient biogenesis of mRNAs or by somatic mutation. Truncated polypeptides synthesized from these aberrant transcripts could be toxic to normal cellular functions. However, mamm...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Korean Society for Biochemistry and Molecular Biology
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4133823/ https://ncbi.nlm.nih.gov/pubmed/23351378 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2013.46.1.002 |
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