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Premature termination codon readthrough in human cells occurs in novel cytoplasmic foci and requires UPF proteins
Nonsense-mutation-containing messenger ribonucleoprotein particles (mRNPs) transit through cytoplasmic foci called P-bodies before undergoing nonsense-mediated mRNA decay (NMD), a cytoplasmic mRNA surveillance mechanism. This study shows that the cytoskeleton modulates transport of nonsense-mutation...
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| 出版年: | J Cell Sci |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Company of Biologists Ltd
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5612172/ https://ncbi.nlm.nih.gov/pubmed/28743738 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.198176 |
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