Exploitation of Langerhans cells for in vivo DNA vaccine delivery into the lymph nodes

There is no clinically available cancer immunotherapy that exploits Langerhans cells (LCs), the epidermal precursors of dendritic cells that are the natural agent of antigen delivery. We developed a DNA formulation with a polymer and obtained synthetic ‘pathogen-like’ nanoparticles that preferential...

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Bibliografski detalji
Izdano u:Gene Ther
Glavni autori: Tőke, Enikő R., Lőrincz, Orsolya, Csiszovszki, Zsolt, Somogyi, Eszter, Felföldi, Gabriella, Molnár, Levente, Szipőcs, Róbert, Kolonics, Attila, Malissen, Bernard, Lori, Franco, Trocio, Jeffrey, Bakare, Nyasha, Horkay, Ferenc, Romani, Nikolaus, Tripp, Christoph H., Stoitzner, Patrizia, Lisziewicz, Julianna
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7374498/
https://ncbi.nlm.nih.gov/pubmed/24694539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2014.29
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