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Exploitation of Langerhans cells for in vivo DNA vaccine delivery into the lymph nodes
There is no clinically available cancer immunotherapy that exploits Langerhans cells (LCs), the epidermal precursors of dendritic cells that are the natural agent of antigen delivery. We developed a DNA formulation with a polymer and obtained synthetic ‘pathogen-like’ nanoparticles that preferential...
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| Izdano u: | Gene Ther |
|---|---|
| Glavni autori: | , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2014
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7374498/ https://ncbi.nlm.nih.gov/pubmed/24694539 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2014.29 |
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