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Langerhans Cells Come in Waves

It is unclear how the Langerhans cell (LC) network is maintained in adult epidermis. In this issue of Immunity, Seré et al. (2012) show that LCs are replenished in two waves. Monocyte-derived, short-lived LCs come first. A second wave follows, and these LCs of nonmonocytic origin are long-lived.

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Bibliographische Detailangaben
Veröffentlicht in:Immunity
Hauptverfasser: Romani, Nikolaus, Tripp, Christoph H., Stoitzner, Patrizia
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4285563/
https://ncbi.nlm.nih.gov/pubmed/23159223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2012.10.013
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