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Langerhans Cells Come in Waves

It is unclear how the Langerhans cell (LC) network is maintained in adult epidermis. In this issue of Immunity, Seré et al. (2012) show that LCs are replenished in two waves. Monocyte-derived, short-lived LCs come first. A second wave follows, and these LCs of nonmonocytic origin are long-lived.

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Bibliographic Details
Published in:Immunity
Main Authors: Romani, Nikolaus, Tripp, Christoph H., Stoitzner, Patrizia
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4285563/
https://ncbi.nlm.nih.gov/pubmed/23159223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2012.10.013
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