A Peptide Vaccine Candidate Tailored to Individuals' Genetics Mimics the Multi-Targeted T Cell Immunity of COVID-19 Convalescent Subjects

Long-term immunity to coronaviruses likely stems from T cell activity. We present here a novel approach for the selection of immunoprevalent SARS-CoV-2-derived T cell epitopes using an in silico cohort of HLA-genotyped individuals with different ethnicities. Nine 30-mer peptides derived from the fou...

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Bibliografski detalji
Izdano u:Front Genet
Glavni autori: Somogyi, Eszter, Csiszovszki, Zsolt, Molnár, Levente, Lőrincz, Orsolya, Tóth, József, Pattijn, Sofie, Schockaert, Jana, Mazy, Aurélie, Miklós, István, Pántya, Katalin, Páles, Péter, Tőke, Enikő R.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2021
Teme:
Genetics
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8261158/
https://ncbi.nlm.nih.gov/pubmed/34249101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2021.684152
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