Structure and Biological Activity of Pathogen-like Synthetic Nanomedicines

Here we characterize the structure, stability and intracellular mode-of-action of DermaVir nanomedicine that is under clinical development for the treatment of HIV/AIDS. This nanomedicine is comprised of pathogen-like pDNA/PEIm nanoparticles (NPs) having the structure and function resembling spheric...

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Detalhes bibliográficos
Main Authors: Lőrincz, Orsolya, Tőke, Enikő R., Somogyi, Eszter, Horkay, Ferenc, Chandran, Preethi, Douglas, Jack F., Szebeni, János, Lisziewicz, Julianna
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3274662/
https://ncbi.nlm.nih.gov/pubmed/21839051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2011.07.013
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