UGT2B17 modifies drug response in chronic lymphocytic leukaemia

BACKGROUND: High UGT2B17 is associated with poor prognosis in untreated chronic lymphocytic leukaemia (CLL) patients and its expression is induced in non-responders to fludarabine-containing regimens. We examined whether UGT2B17, the predominant lymphoid glucuronosyltransferase, affects leukaemic dr...

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Bibliografski detalji
Izdano u:Br J Cancer
Glavni autori: Allain, Eric P., Rouleau, Michèle, Vanura, Katrina, Tremblay, Sophie, Vaillancourt, Joanie, Bat, Vincent, Caron, Patrick, Villeneuve, Lyne, Labriet, Adrien, Turcotte, Véronique, Le, Trang, Shehata, Medhat, Schnabl, Susanne, Demirtas, Dita, Hubmann, Rainer, Joly-Beauparlant, Charles, Droit, Arnaud, Jäger, Ulrich, Staber, Philipp B., Lévesque, Eric, Guillemette, Chantal
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7374097/
https://ncbi.nlm.nih.gov/pubmed/32418995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-020-0887-6
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