Genetic variations in UGT1A1 and UGT2B7 and endometrial cancer risk

UDP-glucuronosyltransferases (UGTs) are a family of phase II metabolizing enzymes involved in glucuronic acid conjugation of sex-steroid hormones. UGT1A1 and UGT2B7 are expressed in the uterus and involved in conjugation and elimination of estrogens. Chronic exposure to estrogens is associated with...

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Bibliografiske detaljer
Main Authors: McGrath, Monica, Lepine, Johanie, Lee, I-Min, Villeneuve, Lyne, Buring, Julie, Guillemette, Chantal, De Vivo, Immaculata
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667627/
https://ncbi.nlm.nih.gov/pubmed/19352303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FPC.0b013e328323f66c
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