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Telomere length and genetic analyses in population-based studies of endometrial cancer risk

BACKGROUND: Telomeres are protective structures at the ends of linear chromosomes, regulated by a host of associated proteins. When telomeres become dysfunctional genomic instability ensues. The vast majority of cells undergo apoptosis, though a rare cell may survive and become tumorigenic. METHODS:...

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Autori principali: Prescott, Jennifer, McGrath, Monica, Lee, I-Min, Buring, Julie E., De Vivo, Immaculata
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978514/
https://ncbi.nlm.nih.gov/pubmed/20549820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.25328
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