Caricamento...

MDM2 SNP309 Is Associated with Endometrial Cancer Risk

Mouse double-minute 2 homologue (MDM2) is a key negative regulator of p53, a tumor suppressor gene that initiates cell cycle arrest and apoptosis in response to DNA damage and other cellular stresses. A T > G polymorphism found in the promoter region of MDM2 (SNP309) increases MDM2 expression and...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Terry, Kathryn, McGrath, Monica, Lee, I-Min, Buring, Julie, De Vivo, Immaculata
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2728574/
https://ncbi.nlm.nih.gov/pubmed/18398041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-07-2872
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !