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MDM2 SNP309 Is Associated with Endometrial Cancer Risk
Mouse double-minute 2 homologue (MDM2) is a key negative regulator of p53, a tumor suppressor gene that initiates cell cycle arrest and apoptosis in response to DNA damage and other cellular stresses. A T > G polymorphism found in the promoter region of MDM2 (SNP309) increases MDM2 expression and...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2728574/ https://ncbi.nlm.nih.gov/pubmed/18398041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-07-2872 |
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