Alternative promoters control UGT2B17-dependent androgen catabolism in prostate cancer and its influence on progression

BACKGROUND: Perturbation of the major UGT2B17-dependent androgen catabolism pathway has the potential to affect prostate cancer (PCa) progression. The objective was to evaluate UGT2B17 protein expression in primary tumours in relation to hormone levels, disease characteristics and cancer evolution....

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Udgivet i:Br J Cancer
Main Authors: Lévesque, Eric, Labriet, Adrien, Hovington, Hélène, Allain, Éric P., Melo-Garcia, Luciana, Rouleau, Michèle, Brisson, Hervé, Turcotte, Véronique, Caron, Patrick, Villeneuve, Lyne, Leclercq, Mickaël, Droit, Arnaud, Audet-Walsh, Etienne, Simonyan, David, Fradet, Yves, Lacombe, Louis, Guillemette, Chantal
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7109100/
https://ncbi.nlm.nih.gov/pubmed/32047296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-020-0749-2
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