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Inhibition of miR-21 regulates mutant KRAS effector pathways and intercepts pancreatic ductal adenocarcinoma development
Almost all pancreatic ductal adenocarcinomas (PDA) develop following KRAS activation which triggers epithelial transformation and recruitment of desmoplastic stroma through additional transcriptional and epigenetic regulation, but only a few of these regulatory mechanisms have been described. We pro...
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| Publicado no: | Cancer Prev Res (Phila) |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7372516/ https://ncbi.nlm.nih.gov/pubmed/32409593 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-20-0053 |
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