Endogenous neurotoxin-like protein Ly6H inhibits alpha7 nicotinic acetylcholine receptor currents at the plasma membrane

α7 nicotinic acetylcholine receptors (nAChRs) are widely expressed in the central nervous system and regarded as potential therapeutic targets for neurodegenerative conditions, such as Alzheimer’s disease and schizophrenia. Yet, despite the assumed pathophysiological importance of the α7 nAChR, mole...

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Publicat a:Sci Rep
Autors principals: Moriwaki, Yasuhiro, Kubo, Natsuki, Watanabe, Mizuho, Asano, Shinsuke, Shinoda, Tomoki, Sugino, Taro, Ichikawa, Daiju, Tsuji, Shoutaro, Kato, Fusao, Misawa, Hidemi
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7371702/
https://ncbi.nlm.nih.gov/pubmed/32686737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-68947-7
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