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Endogenous neurotoxin-like protein Ly6H inhibits alpha7 nicotinic acetylcholine receptor currents at the plasma membrane

α7 nicotinic acetylcholine receptors (nAChRs) are widely expressed in the central nervous system and regarded as potential therapeutic targets for neurodegenerative conditions, such as Alzheimer’s disease and schizophrenia. Yet, despite the assumed pathophysiological importance of the α7 nAChR, mole...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Moriwaki, Yasuhiro, Kubo, Natsuki, Watanabe, Mizuho, Asano, Shinsuke, Shinoda, Tomoki, Sugino, Taro, Ichikawa, Daiju, Tsuji, Shoutaro, Kato, Fusao, Misawa, Hidemi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7371702/
https://ncbi.nlm.nih.gov/pubmed/32686737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-68947-7
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