IL-22/STAT3-Induced Increases in SLURP1 Expression within Psoriatic Lesions Exerts Antimicrobial Effects against Staphylococcus aureus

BACKGROUND: SLURP1 is the causal gene for Mal de Meleda (MDM), an autosomal recessive skin disorder characterized by diffuse palmoplantar keratoderma and transgressive keratosis. Moreover, although SLURP1 likely serves as an important proliferation/differentiation factor in keratinocytes, the possib...

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Udgivet i:PLoS One
Main Authors: Moriwaki, Yasuhiro, Takada, Kiyoko, Nagasaki, Toshinori, Kubo, Natsuki, Ishii, Tomohiro, Kose, Kazuaki, Kageyama, Taihei, Tsuji, Shoutaro, Kawashima, Koichiro, Misawa, Hidemi
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4608685/
https://ncbi.nlm.nih.gov/pubmed/26474319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140750
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