IL-22/STAT3-Induced Increases in SLURP1 Expression within Psoriatic Lesions Exerts Antimicrobial Effects against Staphylococcus aureus

BACKGROUND: SLURP1 is the causal gene for Mal de Meleda (MDM), an autosomal recessive skin disorder characterized by diffuse palmoplantar keratoderma and transgressive keratosis. Moreover, although SLURP1 likely serves as an important proliferation/differentiation factor in keratinocytes, the possib...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Moriwaki, Yasuhiro, Takada, Kiyoko, Nagasaki, Toshinori, Kubo, Natsuki, Ishii, Tomohiro, Kose, Kazuaki, Kageyama, Taihei, Tsuji, Shoutaro, Kawashima, Koichiro, Misawa, Hidemi
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4608685/
https://ncbi.nlm.nih.gov/pubmed/26474319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140750
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