Identification of mesothelioma-specific sialylated epitope recognized with monoclonal antibody SKM9-2 in a mucin-like membrane protein HEG1

The anti-mesothelioma mAb SKM9-2 recognizes the sialylated protein HEG homolog 1 (HEG1). HEG1 is a 400 kDa mucin-like membrane protein found on mesothelioma. SKM9-2 can detect mesothelioma more specifically and sensitively than other antibodies against current mesothelioma markers; therefore, SKM9-2...

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Vydáno v:Sci Rep
Hlavní autoři: Matsuura, Rieko, Kaji, Hiroyuki, Tomioka, Azusa, Sato, Takashi, Narimatsu, Hisashi, Moriwaki, Yasuhiro, Misawa, Hidemi, Imai, Kohzoh, Tsuji, Shoutaro
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6155162/
https://ncbi.nlm.nih.gov/pubmed/30250045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-32534-8
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