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Endogenous neurotoxin-like protein Ly6H inhibits alpha7 nicotinic acetylcholine receptor currents at the plasma membrane

α7 nicotinic acetylcholine receptors (nAChRs) are widely expressed in the central nervous system and regarded as potential therapeutic targets for neurodegenerative conditions, such as Alzheimer’s disease and schizophrenia. Yet, despite the assumed pathophysiological importance of the α7 nAChR, mole...

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Publicado en:Sci Rep
Main Authors: Moriwaki, Yasuhiro, Kubo, Natsuki, Watanabe, Mizuho, Asano, Shinsuke, Shinoda, Tomoki, Sugino, Taro, Ichikawa, Daiju, Tsuji, Shoutaro, Kato, Fusao, Misawa, Hidemi
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7371702/
https://ncbi.nlm.nih.gov/pubmed/32686737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-68947-7
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