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Monobodies as enabling tools for structural and mechanistic biology
Monobodies, built with the scaffold of the fibronectin type III domain, are among the most well-established synthetic binding proteins. They promote crystallization of challenging molecular systems. They have strong tendency to bind to functional sites and thus serve as drug-like molecules that pert...
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| Published in: | Curr Opin Struct Biol |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2020
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7370805/ https://ncbi.nlm.nih.gov/pubmed/32145686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2020.01.015 |
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