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Monobodies as enabling tools for structural and mechanistic biology

Monobodies, built with the scaffold of the fibronectin type III domain, are among the most well-established synthetic binding proteins. They promote crystallization of challenging molecular systems. They have strong tendency to bind to functional sites and thus serve as drug-like molecules that pert...

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Detalhes bibliográficos
Publicado no:Curr Opin Struct Biol
Main Authors: Hantschel, Oliver, Biancalana, Matthew, Koide, Shohei
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7370805/
https://ncbi.nlm.nih.gov/pubmed/32145686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2020.01.015
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