Quantitative Ultrastructural Morphometry and Gene Expression of mTOR-Related Mitochondriogenesis within Glioblastoma Cells

In glioblastoma (GBM) cells, an impairment of mitochondrial activity along with autophagy suppression occurs. Autophagy suppression in GBM promotes stemness, invasion, and poor prognosis. The autophagy deficit seems to be due, at least in part, to an abnormal up-regulation of the mammalian target of...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Ferese, Rosangela, Lenzi, Paola, Fulceri, Federica, Biagioni, Francesca, Fabrizi, Cinzia, Gambardella, Stefano, Familiari, Pietro, Frati, Alessandro, Limanaqi, Fiona, Fornai, Francesco
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7370179/
https://ncbi.nlm.nih.gov/pubmed/32604996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21134570
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