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Promiscuous Roles of Autophagy and Proteasome in Neurodegenerative Proteinopathies

Alterations in autophagy and the ubiquitin proteasome system (UPS) are commonly implicated in protein aggregation and toxicity which manifest in a number of neurological disorders. In fact, both UPS and autophagy alterations are bound to the aggregation, spreading and toxicity of the so-called prion...

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Main Authors: Fiona Limanaqi, Francesca Biagioni, Stefano Gambardella, Pietro Familiari, Alessandro Frati, Francesco Fornai
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2020-04-01
Series:International Journal of Molecular Sciences
Assuntos:
tau
FUS
Acceso en liña:https://www.mdpi.com/1422-0067/21/8/3028
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