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Quantitative Ultrastructural Morphometry and Gene Expression of mTOR-Related Mitochondriogenesis within Glioblastoma Cells

In glioblastoma (GBM) cells, an impairment of mitochondrial activity along with autophagy suppression occurs. Autophagy suppression in GBM promotes stemness, invasion, and poor prognosis. The autophagy deficit seems to be due, at least in part, to an abnormal up-regulation of the mammalian target of...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Ferese, Rosangela, Lenzi, Paola, Fulceri, Federica, Biagioni, Francesca, Fabrizi, Cinzia, Gambardella, Stefano, Familiari, Pietro, Frati, Alessandro, Limanaqi, Fiona, Fornai, Francesco
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7370179/
https://ncbi.nlm.nih.gov/pubmed/32604996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21134570
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