Quantitative Ultrastructural Morphometry and Gene Expression of mTOR-Related Mitochondriogenesis within Glioblastoma Cells

In glioblastoma (GBM) cells, an impairment of mitochondrial activity along with autophagy suppression occurs. Autophagy suppression in GBM promotes stemness, invasion, and poor prognosis. The autophagy deficit seems to be due, at least in part, to an abnormal up-regulation of the mammalian target of...

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Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Ferese, Rosangela, Lenzi, Paola, Fulceri, Federica, Biagioni, Francesca, Fabrizi, Cinzia, Gambardella, Stefano, Familiari, Pietro, Frati, Alessandro, Limanaqi, Fiona, Fornai, Francesco
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7370179/
https://ncbi.nlm.nih.gov/pubmed/32604996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21134570
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