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Quantitative Ultrastructural Morphometry and Gene Expression of mTOR-Related Mitochondriogenesis within Glioblastoma Cells

In glioblastoma (GBM) cells, an impairment of mitochondrial activity along with autophagy suppression occurs. Autophagy suppression in GBM promotes stemness, invasion, and poor prognosis. The autophagy deficit seems to be due, at least in part, to an abnormal up-regulation of the mammalian target of...

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Dades bibliogràfiques
Publicat a:Int J Mol Sci
Autors principals: Ferese, Rosangela, Lenzi, Paola, Fulceri, Federica, Biagioni, Francesca, Fabrizi, Cinzia, Gambardella, Stefano, Familiari, Pietro, Frati, Alessandro, Limanaqi, Fiona, Fornai, Francesco
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7370179/
https://ncbi.nlm.nih.gov/pubmed/32604996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21134570
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