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mTOR-Related Cell-Clearing Systems in Epileptic Seizures, an Update

Recent evidence suggests that autophagy impairment is implicated in the epileptogenic mechanisms downstream of mTOR hyperactivation. This holds true for a variety of genetic and acquired epileptic syndromes besides malformations of cortical development which are classically known as mTORopathies. Au...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Limanaqi, Fiona, Biagioni, Francesca, Busceti, Carla Letizia, Fabrizi, Cinzia, Frati, Alessandro, Fornai, Francesco
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7084443/
https://ncbi.nlm.nih.gov/pubmed/32121250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21051642
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