G6PC2 confers protection against hypoglycemia upon ketogenic diet feeding and prolonged fasting

OBJECTIVE: G6PC2 is predominantly expressed in pancreatic islet beta cells. G6PC2 hydrolyzes glucose-6-phosphate to glucose and inorganic phosphate, thereby creating a futile substrate cycle that opposes the action of glucokinase. This substrate cycle determines the sensitivity of glucose-stimulated...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Mol Metab
Hoofdauteurs: Bosma, Karin J., Rahim, Mohsin, Oeser, James K., McGuinness, Owen P., Young, Jamey D., O'Brien, Richard M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2020
Onderwerpen:
Brief Communication
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7369601/
https://ncbi.nlm.nih.gov/pubmed/32569842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2020.101043
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items