Lanean...
Mechanism of β-arrestin recruitment by the μ-opioid G protein-coupled receptor
Agonists to the μ-opioid G protein-coupled receptor (μOR) can alleviate pain through activation of G protein signaling, but they can also induce β-arrestin activation, leading to such side effects as respiratory depression. Biased ligands to μOR that induce G protein signaling without inducing β-arr...
Gorde:
| Argitaratua izan da: | Proc Natl Acad Sci U S A |
|---|---|
| Egile Nagusiak: | , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
National Academy of Sciences
2020
|
| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7368253/ https://ncbi.nlm.nih.gov/pubmed/32601232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1918264117 |
| Etiketak: |
Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!
|