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β-arrestins and G Protein-Coupled Receptor Trafficking
Non-visual arrestins (β-arrestin-1 and β-arrestin-2) are adaptor proteins that function to regulate G protein-coupled receptor (GPCR) signaling and trafficking. β-arrestins are ubiquitously expressed and function to inhibit GPCR/G protein coupling, a process called desensitization, and promote GPCR...
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Publicado no: | Handb Exp Pharmacol |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4513654/ https://ncbi.nlm.nih.gov/pubmed/24292830 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-3-642-41199-1_9 |
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