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Targeting G protein-coupled receptor kinases (GRKs) to G protein-coupled receptors
G protein-coupled receptors (GPCRs) interact with three protein families following agonist binding: heterotrimeric G proteins, G protein-coupled receptor kinases (GRKs) and arrestins. GRK-mediated phosphorylation of GPCRs promotes arrestin binding to uncouple the receptor from G protein, a process c...
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| Publicado no: | Curr Opin Endocr Metab Res |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7945687/ https://ncbi.nlm.nih.gov/pubmed/33718657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coemr.2020.09.002 |
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