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G-protein coupled receptor kinases (GRKs) as Therapeutic Targets in Cardiovascular Disease

G protein-coupled receptors (GPCRs) represent the largest family of membrane receptors and are responsible for regulating a wide variety of physiological processes. This is accomplished via ligand binding to GPCRs, activating associated heterotrimeric G proteins and intracellular signaling pathways....

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Hlavní autoři: Belmonte, Stephen L., Blaxall, Burns C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3146028/
https://ncbi.nlm.nih.gov/pubmed/21778435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.110.231233
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