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Depression of Mitochondrial Function in the Rat Skeletal Muscle Model of Myofascial Pain Syndrome Is Through Down-Regulation of the AMPK-PGC-1α-SIRT3 Axis

PURPOSE: The causative mechanisms triggering myofascial pain syndrome (MPS) are still in debate. It is becoming evident that mitochondrial dysfunction may regulate pathways controlling MPS. The aim of this study was to investigate whether AMPK-PGC-1α-SIRT3 axis is associated with depression of mitoc...

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Dettagli Bibliografici
Pubblicato in:J Pain Res
Autori principali: Ye, Le, Li, Mingli, Wang, Zhankui, Yang, Zhongwei, Zhang, Jinyuan, Fang, Hongwei, He, Zhenzhou, Wang, Xiangrui
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7367922/
https://ncbi.nlm.nih.gov/pubmed/32765049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JPR.S233583
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