Leishmania infantum Modulates Host Macrophage Mitochondrial Metabolism by Hijacking the SIRT1-AMPK Axis

Metabolic manipulation of host cells by intracellular pathogens is currently recognized to play an important role in the pathology of infection. Nevertheless, little information is available regarding mitochondrial energy metabolism in Leishmania infected macrophages. Here, we demonstrate that durin...

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Detalles Bibliográficos
Publicado en:PLoS Pathog
Main Authors: Moreira, Diana, Rodrigues, Vasco, Abengozar, Maria, Rivas, Luis, Rial, Eduardo, Laforge, Mireille, Li, Xiaoling, Foretz, Marc, Viollet, Benoit, Estaquier, Jérôme, Cordeiro da Silva, Anabela, Silvestre, Ricardo
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4349736/
https://ncbi.nlm.nih.gov/pubmed/25738568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004684
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