Leishmania infantum Modulates Host Macrophage Mitochondrial Metabolism by Hijacking the SIRT1-AMPK Axis

Metabolic manipulation of host cells by intracellular pathogens is currently recognized to play an important role in the pathology of infection. Nevertheless, little information is available regarding mitochondrial energy metabolism in Leishmania infected macrophages. Here, we demonstrate that durin...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS Pathog
Egile Nagusiak: Moreira, Diana, Rodrigues, Vasco, Abengozar, Maria, Rivas, Luis, Rial, Eduardo, Laforge, Mireille, Li, Xiaoling, Foretz, Marc, Viollet, Benoit, Estaquier, Jérôme, Cordeiro da Silva, Anabela, Silvestre, Ricardo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2015
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4349736/
https://ncbi.nlm.nih.gov/pubmed/25738568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004684
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