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Depression of Mitochondrial Function in the Rat Skeletal Muscle Model of Myofascial Pain Syndrome Is Through Down-Regulation of the AMPK-PGC-1α-SIRT3 Axis

PURPOSE: The causative mechanisms triggering myofascial pain syndrome (MPS) are still in debate. It is becoming evident that mitochondrial dysfunction may regulate pathways controlling MPS. The aim of this study was to investigate whether AMPK-PGC-1α-SIRT3 axis is associated with depression of mitoc...

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Vydáno v:J Pain Res
Hlavní autoři: Ye, Le, Li, Mingli, Wang, Zhankui, Yang, Zhongwei, Zhang, Jinyuan, Fang, Hongwei, He, Zhenzhou, Wang, Xiangrui
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7367922/
https://ncbi.nlm.nih.gov/pubmed/32765049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JPR.S233583
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