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Activation and inhibition of nonsense-mediated mRNA decay control the abundance of alternative polyadenylation products
Alternative polyadenylation (APA) produces transcript 3′ untranslated regions (3′UTRs) with distinct sequences, lengths, stabilities and functions. We show here that APA products include a class of cryptic nonsense-mediated mRNA decay (NMD) substrates with extended 3′UTRs that gene- or transcript-le...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7367170/ https://ncbi.nlm.nih.gov/pubmed/32542372 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa491 |
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