Alternative Polyadenylation and Nonsense-Mediated Decay Coordinately Regulate the Human HFE mRNA Levels

Nonsense-mediated decay (NMD) is an mRNA surveillance pathway that selectively recognizes and degrades defective mRNAs carrying premature translation-termination codons. However, several studies have shown that NMD also targets physiological transcripts that encode full-length proteins, modulating t...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Martins, Rute, Proença, Daniela, Silva, Bruno, Barbosa, Cristina, Silva, Ana Luísa, Faustino, Paula, Romão, Luísa
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2012
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3329446/
https://ncbi.nlm.nih.gov/pubmed/22530027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035461
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы