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Differential HFE Gene Expression Is Regulated by Alternative Splicing in Human Tissues

BACKGROUND: The pathophysiology of HFE-derived Hereditary Hemochromatosis and the function of HFE protein in iron homeostasis remain uncertain. Also, the role of alternative splicing in HFE gene expression regulation and the possible function of the corresponding protein isoforms are still unknown....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Martins, Rute, Silva, Bruno, Proença, Daniela, Faustino, Paula
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048171/
https://ncbi.nlm.nih.gov/pubmed/21407826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017542
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