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Prolongation of metallothionein induction combats Aß and α-synuclein toxicity in aged transgenic Caenorhabditis elegans

Neurodegenerative disorders (ND) like Alzheimer’s (AD), Parkinson’s (PD), Huntington’s or Prion diseases share similar pathological features. They are all age dependent and are often associated with disruptions in analogous metabolic processes such as protein aggregation and oxidative stress, both o...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Pretsch, Dagmar, Rollinger, Judith Maria, Schmid, Axel, Genov, Miroslav, Wöhrer, Teresa, Krenn, Liselotte, Moloney, Mark, Kasture, Ameya, Hummel, Thomas, Pretsch, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7366685/
https://ncbi.nlm.nih.gov/pubmed/32678125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-68561-7
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