Prolongation of metallothionein induction combats Aß and α-synuclein toxicity in aged transgenic Caenorhabditis elegans

Neurodegenerative disorders (ND) like Alzheimer’s (AD), Parkinson’s (PD), Huntington’s or Prion diseases share similar pathological features. They are all age dependent and are often associated with disruptions in analogous metabolic processes such as protein aggregation and oxidative stress, both o...

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Publicat a:Sci Rep
Autors principals: Pretsch, Dagmar, Rollinger, Judith Maria, Schmid, Axel, Genov, Miroslav, Wöhrer, Teresa, Krenn, Liselotte, Moloney, Mark, Kasture, Ameya, Hummel, Thomas, Pretsch, Alexander
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7366685/
https://ncbi.nlm.nih.gov/pubmed/32678125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-68561-7
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