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A robust and miniaturized screening platform to study natural products affecting metabolism and survival in Caenorhabditis elegans

In this study a robust, whole organism screening based on Caenorhabditis elegans is presented for the discovery of natural products (NP) with beneficial effects against obesity and age-related diseases. Several parameters of the elaborated workflow were optimized to be adapted for probing multicompo...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zwirchmayr, Julia, Kirchweger, Benjamin, Lehner, Theresa, Tahir, Ammar, Pretsch, Dagmar, Rollinger, Judith M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7378205/
https://ncbi.nlm.nih.gov/pubmed/32704017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-69186-6
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